Ontario

Toronto developer of IronCAP, a post-quantum cryptography product line covering email, remote access and blockchain, alongside a legacy secure remote-access business. Renamed from 01 Communique Laboratory in 2025.

Toronto company selling Rho, a Health Canada-licensed, FDA De Novo-cleared AI system that screens routine x-rays for low bone mineral density, plus Physis, an AI pediatric bone-age assessment tool.

Toronto-based developer of credential and access management software, spanning password and secrets vaults, SaaS application management, and governance of access held by employees, machines and AI agents.

Toronto company building the ALTA Platform with SmartMoov, a robotic patient-transfer device with AI-based collision avoidance and patient-presence detection that lets one caregiver move immobile patients.

Kitchener company selling LinePulse, an industrial-AI manufacturing quality analytics platform that gives automotive and other discrete manufacturers real-time SPC monitoring and root-cause analysis.

An AI-native platform that deploys autonomous AI agents to automate customer service conversations across chat, voice and email channels.

Kanata, Ontario defence company developing software-defined electronic warfare systems: a digital-beamforming counter-drone jammer, a drone-mounted EW payload, a multi-function spectrum sensing and attack system, and command software for spectrum operations.

Toronto company selling Aide, a governed agentic AI platform that resolves customer-service conversations end-to-end inside existing helpdesks such as Zendesk, Front and Gorgias, with human oversight tools.

Designs and builds wind tunnels and environmental test facilities, including low-speed, transonic, trisonic and cryogenic aeronautical tunnels, icing tunnels, acoustic chambers and ground runup enclosures.

Builds software that fuses radar, RF, optical, ADS-B and Remote ID data to manage low-altitude airspace, authorize drone flights, and detect and track uncooperative aerial objects.

Toronto company selling IPRO, an AI model that generates survival predictions from routine CT scans to accelerate drug efficacy evaluation in oncology clinical trials.

Toronto company that owns and operates two colocation data-centre suites, TOR1 and TOR2, at 151 Front Street West. From them it sells rack space, dedicated bare-metal servers, unmetered IP transit and private connections to public clouds.

Ottawa company selling the ANVIL platform, which structures and AI-enriches intelligence, operations and planning data for Canadian and allied defence and national-security decision-making.

Waterloo developer of state-space-model AI for edge devices, licensing speech-to-text and text-to-speech software and selling the TSP1 accelerator ASIC for low-power on-device voice and sensor inference.

Toronto company selling Armilla Guaranteed, a third-party AI model verification and warranty platform that certifies AI systems for accuracy, fairness and robustness, with insurer-backed financial protection if a model underperforms.

Toronto enterprise documentation company spun out of Deloitte in 2020, where the product was known as dTrax. Sells a platform that generates contracts, extracts their data and manages documentation workflows for banks and financial institutions.

Kitchener company selling Asenion, an AI governance, risk and compliance platform (formerly Fairly AI) that tests, red-teams and monitors AI systems for EU AI Act, ISO/IEC 42001 and NIST AI RMF compliance.

Toronto company developing backup and recovery software: the agentless Tigris platform for servers, VMs and databases, the multi-tenant SaaSAssure service for SaaS application data, and Backup2Cloud, a backup service sold through MSPs.

Kitchener company building a reinforcement-learning platform that automates analog and mixed-signal chip layout, generating thousands of optimized physical layouts for high-speed SERDES interconnects.

Cambridge, Ontario designer and builder of automated assembly, test and packaging systems for manufacturers, with its own automation platforms including SuperTrak linear-mover conveyance and Symphoni assembly technology.

Toronto company selling ACP Electrical, a spatial-AI platform that generates clash-free, fully coordinated electrical models for buildings such as data centres, hospitals and schools in hours instead of weeks.

Ottawa company building a multi-tenant SaaS platform that lets managed service providers audit, baseline, monitor and remediate Microsoft 365 security settings and detect breaches across all of their client tenants.

Waterloo company selling cloud-based network management software that automatically discovers, maps and monitors network devices, servers, endpoints and SaaS applications for managed service providers and corporate IT teams.

Kitchener-based designer and manufacturer of autonomous floor-scrubbing robots - Neo, Neo 2W and Kas - that clean commercial and industrial floors and are managed through a fleet software platform.

Waterloo company selling an AI-powered frontline enablement platform that combines microlearning, guided execution and performance insight for shift workers, with an AI assistant and coach built into the product.

Toronto company selling Azoma, an agentic commerce optimization platform that tracks and improves brand visibility across AI shopping agents, and Ecomtent, its AI product-content generation tool.

Ottawa-area company selling Backboard, a memory-native API that gives developers persistent, cross-model memory and orchestration across more than 2,000 LLMs, plus model optimization and a code-generation studio.

Builds AI software (ASCEND, and newly EMET) that helps pharma R&D scientists mine scientific literature and biological data to speed preclinical drug discovery.

Kitchener company selling ProSense, AI-powered optical sensors and software that create 3D images of feed and grain bins to give feed mills, farms and integrators real-time inventory visibility.

Toronto biopharma company that uses large language models to identify failed drug candidates worth reviving, then runs its own clinical trials to bring them to approval for new indications.

Waterloo company with two divisions: Secure Communications, which builds encrypted voice and messaging, unified endpoint management and critical event management software for governments, and QNX, an embedded real-time operating system used in vehicles.

Oshawa company developing passwordless, phishing-resistant authentication: a phone-based security key for office staff, a device-free credential for frontline workers on shared workstations, and a vault for legacy shared credentials.

Toronto company, legally Blue J Legal Inc., selling a tax-research platform that answers US, Canadian and UK tax questions in natural language over a curated library of primary tax law plus Tax Notes and IBFD content, returning source citations.

Toronto company selling enterprise software for core network services — DNS, DHCP and IP address management, known as DDI — combined with network observability, flow and packet analytics and DNS-based security, deployable on-premises, in data centres and across multicloud.

Toronto infectious-disease intelligence company, founded as BioDiaspora and renamed in 2014. Combines automated global data collection with epidemiologist analysis to sell outbreak surveillance, risk assessments and disease forecasting.

Ottawa company developing eID-Me, a mobile app and platform for remote identity verification, a digital ID wallet that keeps encrypted personal data on the user's device, mobile driver's licences, and password-free and multi-factor login.

Ottawa developer of all-analog neural signal processor chips and licensable IP cores built in standard CMOS, aimed at always-on audio, vision and sensor AI inference at the edge with very low power and latency.

Ottawa company selling AI software that optimizes electricity grids, renewable and battery dispatch, data-centre load and EV charging, deployed with Ontario utilities and the City of Summerside, PEI.

Ottawa designer and manufacturer of custom optical components and complete opto-mechanical lens assemblies, from demanding research and development optics to consumable optics produced in the thousands monthly.

Toronto employer-of-record and global payroll company, operating as 4400 WE Technologies Inc. Lets companies hire, contract, pay and manage staff in 170+ countries without local entities, with AI agents built on Cohere's models.

Toronto company selling an AI-native, IoT-enabled construction risk intelligence platform that detects water leaks, monitors concrete curing and tracks environmental hazards on job sites to protect project margins.

Toronto AI-compression company whose ShapeLearn technology learns optimal per-parameter numeric precision to shrink and accelerate large AI models, built on a University of Toronto research group's decade of quantization research.

Ottawa manufacturer of auto-deploying mobile satellite antenna systems sold under the iNetVu brand through a worldwide dealer network, now developing Ka-band electronically steered antennas.

Ottawa-headquartered, TSX-listed mission-critical solutions company focused on defence, space and healthcare: simulation-based military training, MIL-STD defence electronics, satellite ground systems and GNSS antennas.

Developing sovereign Canadian launch vehicles powered by its in-house E-1 methalox engine: the R-1 light-lift pathfinder and the reusable R-2 medium-lift rocket targeting 6,500 kg to low Earth orbit.

Builds lunar and deep-space systems - rovers, flight cameras, avionics and onboard computers - plus ruggedized industrial and defence ground vehicles, from facilities in Bolton and Stratford, Ontario.

Space and defence company developing dual-use micro nuclear reactor platforms for Arctic, remote and lunar power, plus a deep-tech R&D arm. Federally incorporated in 2020 as Canadian Space Mining Corporation and renamed in December 2025. No reactor is in service.

Toronto company, legally Canvass Analytics Inc., selling Knowledge AI — an enterprise platform of role-specific assistants that retrieve and cross-check information across documents and enterprise systems, built on a knowledge graph with retrieval-augmented generation and quantized models.

Mississauga company selling a multi-agent AI platform that structures clinical EMR data to pre-screen patients and accelerate clinical-trial enrollment for cardiometabolic disease studies.

Kitchener company building a data security posture management and attack surface management platform for MSPs and MSSPs that discovers and classifies sensitive data, maps assets, and audits vulnerabilities, configurations and file access.

Toronto company that designs and manufactures data-centre networking switches, storage and compute hardware and integrated racks, mainly for hyperscale and AI customers. Connectivity & Cloud Solutions was 81% of Q2 2026 revenue; the rest is aerospace, industrial and health-tech manufacturing.

Mississauga-headquartered provider of managed cloud, application modernization and data services that operates its own data centres in Mississauga, Toronto and Vancouver, and in the US.

Ottawa company, legally Rockport Networks Inc., that makes composable data-centre infrastructure. Its optical fabric hardware and management software pool GPUs, memory and other components outside individual servers so they can be assigned to workloads anywhere in the data centre.

Toronto company selling a machine-learning platform that turns millions of public documents from 40,000+ cities, utilities and public agencies across North America into predictive sales intelligence on infrastructure projects.

Sudbury, Ontario company building a spec-driven AI development platform that turns a plain-language product description into a PRD and technical spec, then generates production code into the customer's own GitHub repository and deploys it.

Waterloo company licensing WiFi Motion, software that reads ambient wireless signals to detect motion, presence and change in homes and buildings without cameras or wearables, distributed through chipset makers and internet service providers.

Waterloo company developing a static-analysis engine and CLI that scan configuration files across cloud accounts, infrastructure-as-code, containers and applications for security misconfigurations, with compliance-mapped reports and auto-remediation.

Builds large language models and generative AI tools for enterprise use, offered via API and on-premise/private-cloud deployment.

Ottawa company building Cord3 Unity, a data-centric security platform that encrypts individual data objects and enforces policy-based access at an in-network enforcement point, aimed at defence and coalition data sharing.

Toronto company selling CrowdCore, a creator-vetting and discovery platform that uses AI video understanding to help brands and agencies find, vet and shortlist social-media creators.

Designs and manufactures quantum-safe, crypto-agile hardware security modules and secrets-management platforms for governments, financial institutions and infrastructure operators.

Toronto company developing a platform that stores, enriches, shares and continuously monitors software bills of materials (SBOMs) so software makers and buyers can track vulnerabilities across their software supply chain.

Ottawa company developing LoginTC, a multi-factor authentication product that adds push, FIDO2, smart-card and offline authentication to VPNs, Windows logins, remote desktop and web applications, in cloud or on-premises deployments.

Ottawa company that designs and manufactures electromagnetic spectrum hardware and software: ESM/ELINT signals-intelligence receivers, multi-channel radar threat emulators for EW test and training, HF over-the-horizon radar processing, and RF/IF record-and-playback.

Toronto company selling an AI decision platform using reinforcement learning for retail promotion, pricing and assortment optimization, and for insurance fraud detection, claims automation and underwriting.

London, Ontario company selling ATLAS, an AI-powered lung-ultrasound diagnostic platform that runs offline on mobile devices, with FDA 510(k) clearance for its B-line detection model.

Uses an AI foundation-model platform (BioFM, including the BigRNA model) to discover and design RNA and genetic-medicine drug candidates.

Ottawa designer and manufacturer of scientific imaging systems — high-sensitivity CCD and CMOS cameras, filter wheels, adaptive optics and observatory automation equipment — for scientific, industrial, aerospace and OEM applications.

Ottawa company selling DistillerSR, an AI-enabled systematic literature review platform used by pharmaceutical, medical device and research organizations to automate screening, classification and evidence extraction from scientific literature.

Kingston, Ontario company operating the Distributive Compute Platform, a web-stack-based distributed computing network that pools idle CPU and GPU capacity from institutional devices and meters it, with worker clients including browsers, Windows, Linux, Docker and Android.

Ottawa company building AuraNet, a command-and-control and data-fusion platform used with Arctic-hardened sensors for surveillance in remote northern regions, and developing Scout, an uncrewed aircraft designed to fly alongside crewed fighter jets.

Toronto company, legally Ecopia Tech Corporation, applying computer-vision models to high-resolution satellite and aerial imagery to produce vector map layers — building footprints, land cover, roads and geocoded addresses — sold to governments and industry.

Ottawa fabless semiconductor company selling Wi-Fi silicon and licensable IP built on its patented Spectrum Slicing architecture, which runs multiple concurrent channels in a single band, delivered as the PrismIQ product family and reference designs.

Ottawa designer and manufacturer of planar lightwave circuit (PLC) optical chips on silicon — CWDM, DWDM and LWDM multiplexers, switching fabrics and star couplers — sold to transceiver makers serving data centre, telecom and AI markets.

London, Ontario company selling EpiSign METRIC, a clinically validated epigenomic diagnostic testing software that uses machine learning to identify DNA-methylation episignatures linked to rare genetic conditions.

Ottawa developer and manufacturer of aluminum and copper metal powders for additive manufacturing, produced with its own atomization process and aimed at laser powder-bed-fusion production.

Waterloo-based managed detection and response provider operating a 24/7 security operations centre and the Atlas security operations platform for organizations internationally.

Makes quantum-safe cybersecurity software — BasejumpQDN key management for quantum key distribution networks and BasejumpSKI symmetric key infrastructure — plus quantum risk assessments.

Ottawa company selling an enterprise AI meeting assistant and "AI Chief of Staff" that records, transcribes and summarizes meetings, tracks action items, and answers questions across an organization's meeting history.

Toronto company developing a platform that inventories and monitors the scripts, trackers and cookies running on websites and mobile apps, blocks unauthorized ones and generates evidence for PCI DSS, HIPAA and privacy-law compliance.

Kitchener designer and manufacturer of specialty fibre-optic assemblies, bundles, linear and v-groove fibre arrays, probes and hermetic vacuum feedthroughs for spectroscopy, astronomy, LiDAR and biomedical instrumentation.

Ottawa-based developer of managed detection and response software for small and mid-sized businesses and managed service providers, covering endpoint, network and cloud monitoring from one platform.

Designs and manufactures avionics sub-system hardware - backlit cockpit control panels, switch panels, keyboards and cursor control devices - and high-reliability printed circuit boards.

Toronto company (legally Stratosphere Technology Inc.) selling the Fiscal.ai Terminal and API, which turn unstructured global corporate filings into structured, AI-searchable financial data for investors.

Kitchener company selling Origin, an FDA-cleared surgical-drain sensor, and Stream Care, machine-learning software that combines sensor and EHR data to flag postoperative complication risk after GI surgery.

Makes DeepFoqus-Accelerate, software that plugs into existing MRI scanners and uses quantum-derived algorithms and machine learning to reconstruct images from shorter scans.

Toronto company selling an AI-driven sales performance management platform — Forma Operator, Forma Architect and Forma Prophet — for enterprise incentive compensation, territory planning and sales analytics.

Brampton solid-state welding company whose induction-assisted friction welding process joins metal without melting it. It targets pipeline, nuclear, shipbuilding, rail, aerospace and space applications.

Toronto company selling VIOLET, MAGENTA and ROSE, AI tools that assess egg quality for egg freezing, IVF and donor-egg programs at fertility clinics worldwide.

Develops oil-debris and oil-condition monitoring sensors and analyzers that detect metallic wear debris in aircraft engines and gearboxes for condition-based maintenance.

Markham manufacturer of quantum magnetometers and gradiometers — optically pumped potassium, Overhauser and proton precession — for ground, airborne, UAV and observatory use in mineral exploration, earth science and unexploded ordnance detection.

Toronto company selling an AI operating system for insurance brokerages and carriers, built on SMS-native AI agents that handle quoting, underwriting questions, customer conversations and compliance review over text.

Kitchener company selling an AI platform that turns high-resolution geospatial imagery into precise HD maps and simulation-ready environments for autonomous-driving developers, ADAS testing and urban planning.

Guelph-based operator of indoor vertical farms growing pesticide-free microgreens, baby greens and salad mixes for Canadian retail and foodservice customers.

University of Waterloo spin-off that turns satellite and drone Earth-observation data into water and cryosphere products - lake water quality, ice cover and biodiversity dashboards - for government and industry users.

Hamilton company selling Haloo, an AI-driven trademark search and clearance platform for law firms, naming agencies and enterprises.

Guelph, Ontario manufacturer of dry-type transformers, harmonic filters and other power-quality equipment, and, since buying AEG Power Solutions in 2026, UPS and power-conversion systems. Data-centre orders drive much of its recent sales and backlog growth.

Toronto company selling DARWEN, an AI clinical co-pilot platform for early detection of rare, complex and chronic disease, plus SMART Search/SMART Summary health-data-interoperability AI tools.

Builds FATHOM, a quantum-enabled electron paramagnetic resonance spectrometer that uses superconducting quantum sensors to measure protein conformation and dynamics for structural biology.

Developing the Cavorite X7, a seven-seat hybrid-electric VTOL aircraft using patented fan-in-wing technology to take off vertically then fly as a conventional fixed-wing aircraft. Has flown a 50%-scale prototype.

Toronto company selling The Co-Analyst, an AI research tool for institutional investors that answers questions on public-company filings with a no-hallucination guarantee, plus AI-powered screening and forensic risk assessment.

St. Jacobs maker of whole-slide pathology scanners, pairing scanning laser imaging technology commercialized from the University of Waterloo with image-management and AI-assisted analysis software for clinical and research labs.

Toronto-based developer of Advanced Compressed Air Energy Storage facilities that store energy using compressed air and water for eight or more hours of grid-scale discharge.

Designs, certifies and manufactures aircraft modifications and mission systems - ISR operator consoles, EO/IR mounts, medevac interiors, avionics retrofits and cargo systems - for fixed-wing, rotary-wing and uncrewed platforms.

Waterloo designer and manufacturer of desktop atomic force microscopes built on a single-chip MEMS AFM, together with a semiconductor metrology system for detecting nanometre-scale defects on wafers.

Toronto generative AI company building text-to-image foundation models known for rendering legible text in images. Ships a consumer app, an API, enterprise custom models and the open-weight Ideogram 4.0.

Hamilton company selling Proof of Inference, a zero-knowledge cryptographic protocol that verifies AI model outputs for autonomous agents, robotics and other AI systems.

Designs and manufactures uncrewed aerial vehicles and mission systems, including OMEN, a long-range hybrid-electric VTOL uncrewed aircraft for intelligence, surveillance and reconnaissance.

Kanata developer of indium-phosphide electro-absorption modulated laser chips that monolithically integrate high-speed electronics and photonics on one substrate, for data-centre and AI optical links at 100G and 200G per lane.

Halton Hills manufacturer of high-vacuum thin-film deposition and etching equipment, including physical vapour deposition systems, ion beam sputter and etch tools, magnetron sputtering and plasma-enhanced CVD for diamond-like carbon.

Toronto company selling Valiant, an AI-and-robotics platform that autonomously designs, tests and optimizes pharmaceutical formulations for drug developers.

Toronto company selling iVOD, iAID and iFlow, patented computer-vision products that count vehicle occupancy, detect road incidents and track people and vehicle flow for transportation and infrastructure operators.

Waterloo-based cybersecurity firm selling quantum-safe cryptography software: ISARA Radiate (post-quantum algorithm toolkit) and ISARA Advance (cryptographic inventory and risk assessment).

Waterloo developer of X-ray detectors and imaging systems built on its own amorphous-selenium detector technology, including single-exposure dual-energy spectral flat panels and phase-contrast micro-CT.

Satellite telecommunications company building an optical data-relay constellation that acts as Internet exchange points in orbit for space-to-space and space-to-ground connectivity.

Ottawa company selling Maestro, which it describes as an AI-infused end-to-end supply chain orchestration platform connecting planning, procurement, manufacturing and logistics, sold by subscription to large enterprises.

Toronto company selling an AI platform for structured behavioural interviews and skills assessment, using machine-learning scoring trained on objective competency data to reduce bias in hiring and student placement.

Waterloo company selling Bottlenose, AI-enabled stereo/monocular smart cameras, and Snow Flea, a distributed multispectral sensing network for critical-infrastructure and Arctic surveillance.

Ottawa company developing Larus Foresight, AI/ML decision-support software that fuses sensor and intelligence data, generates adversary and friendly courses of action, and plans ISR collection for army, navy and joint operations.

Toronto company selling an agentic healthcare experience platform, Forge by League, built on its own healthcare small language models, that payers, providers and consumer health organizations use to deliver member-facing digital experiences.

Ottawa manufacturer of precision optics, etalons and coatings, excimer and TEA CO2 lasers, and VIPA-based high-resolution spectrometers. An enabling supplier whose instruments are applied to quantum optics, not a quantum computing developer.

Toronto company, legally Private AI Inc. and rebranded to Limina in March 2026, selling container-deployed machine-learning software that detects, redacts, pseudonymises or replaces personal and health data in text, documents, images and audio across 52 languages.

Ottawa company building Neurosymbolic Loon AI — Loon Lens and Loon Waters — agentic software that automates systematic literature screening and forecasts drug reimbursement decisions for health technology assessment and market-access teams.

Builds confidential AI infrastructure: its Lorica.ai platform runs AI models in hardware-backed, attested confidential-computing environments, alongside its earlier Private Pursuit platform built on fully homomorphic encryption.

Toronto company selling VIBE and Resonance Rx, AI-curated therapeutic music apps that use reinforcement learning and facial-expression-based "Emotion AI" to target anxiety, stress and dementia-related agitation.

Hamilton, Ontario company developing medical systems for spaceflight and austere environments, including the Connected Care Medical Module, a deployable digital care suite for remote communities and space missions.

Toronto company (formerly Knowtions Research) selling ORCA, an enterprise AI platform that turns voice/file inputs into structured work product — reports, graphs and optimization plans — for content, legal-discovery and logistics workflows.

Waterloo, Ontario company that builds PASE, a land-based high-frequency surface wave radar that tracks vessels over the horizon out to the 200-nautical-mile EEZ, and TimeCaster, software that fuses radar and AIS feeds to track ships and flag threats.

TSX-listed Ontario manufacturer of aeroengine and aerostructure components for commercial and defence aircraft, with a Winnipeg space division building small satellite buses, avionics and Black Brant rockets.

Toronto company building software that predicts and helps satellite operators avoid radio-frequency interference, now positioned as a unified intelligence platform aggregating space, Earth, ISR and spectrum data.

Waterloo company developing digital forensics and incident-response software that acquires, analyzes and reports on evidence from computers, mobile devices, cloud services and vehicles, used by police, government agencies and corporate security teams.

Waterloo company selling MAJiK Visual Factory, IoT Connect and Enterprise Connect, which connect PLCs to auto-classify downtime and generate AI-driven continuous-improvement guidance for manufacturers.

Space technology company building space robotics, satellite systems, and Earth observation and geointelligence systems for commercial and government missions.

Designs and builds turnkey gas-turbine engine and engine-component test facilities and the nxDAS data-acquisition and control systems that run them, for aero-engine makers, MROs and research institutions.

Prescott, Ontario maker of precision electrical metrology instruments for national measurement institutes and calibration labs, including the 6820T cryogen-free quantum Hall resistance system and a cryogenic current comparator bridge.

Ottawa company building a zero-trust data mesh for operational technology networks: edge software and gateways that ingest sensor data, quantum-safe encryption for data streams, and a peer-to-peer network that routes that data to authorized users in critical infrastructure and defence.

Makes an AI-driven financial oversight platform that continuously analyzes 100% of transactions in accounting/ERP systems to flag anomalies, errors, and fraud risk for auditors and finance teams.

Kitchener-based builder of traffic data collection and signal management systems for cities, using sensors, cloud software and computer vision to help municipal transportation agencies monitor intersections and manage road networks.

Develops flight and ground software for space robotics and autonomy - the Spacefarer operations platform and Spacefarer AI for onboard machine learning - and builds lunar rovers for agency and commercial missions.

Waterloo developer of millimetre-wave and sub-terahertz beamforming integrated circuits and multi-antenna transceiver systems for 4D imaging radar, satellite phased arrays and 5G/6G radio front-ends.

Toronto company selling Marey, a video-generation foundation model trained only on licensed footage, aimed at professional filmmakers who need frame-accurate camera, motion and lighting control.

Toronto builder of automated fused-filament 3D printing systems - Array, Element, Orion and Palette X - together with production polymer materials and print-management software for factory-floor part production.

Toronto company selling Mycroft, an agentic AI platform that automates governance, risk and compliance work — monitoring cloud infrastructure, enforcing policy and preparing companies for security audits.

Etobicoke, Ontario manufacturer of high-reliability RF, microwave and millimetre-wave assemblies for satellites, avionics, defence and radar, including transmit-receive assemblies flying on the OneWeb constellation.

Builds NetraAI, a machine-learning platform that analyzes clinical trial datasets to identify patient subpopulations and patterns in treatment efficacy, toxicity and placebo response for drug sponsors.

Toronto developer and licensor of purpose-built silicon interface IP, including UCIe-Advanced and UCIe-Standard PHY and die-to-die adapter cores for chiplet, AI, high-performance computing and 5G infrastructure designs.

Hamilton company building an AI decision-support platform that gives real-time lymph-node staging guidance for lung cancer during EBUS-TBNA ultrasound procedures.

Ottawa company selling an AI-powered ecommerce operations platform that deploys AI agents to detect and prioritize revenue-impacting site errors, and to optimize performance, accessibility and conversion for online retailers.

Builds Canadian orbital launch vehicles (Tundra, Tempest), 3D-printed liquid rocket engines, small satellites and in-space propulsion, and is developing the Atlantic Spaceport Complex in Newfoundland and Labrador.

Ottawa company developing TITAN BY NORTAC, a command-and-control and situational-awareness platform that fuses tracking and messaging from satellite, cellular and radio devices, alongside its own satellite tracking device and mobile apps.

Oakville, Ontario defence-technology company whose FIXAIT edge AI detection engine won a $375,000 prize at National Defence's 2025 Counter-Uncrewed Aerial Systems Sandbox. It also lists interceptor, strike and modular UAS platforms and field avionics.

Ottawa developer of autonomous rendezvous, proximity operations and docking software and hardware for on-orbit satellite servicing, inspection and debris capture, demonstrated on ISS Astrobee free-flying robots.

Toronto company selling ODAIA Field Intelligence and Marketing Intelligence, AI platforms that prioritize and sequence pharma sales-rep and marketing engagement with healthcare providers inside Veeva CRM.

Toronto company selling OnX, an AI software platform that analyzes raw ultrasound signals from point-of-care devices to screen for structural liver disease.

A Canadian non-profit building the world's first open-source, full-stack trapped-ion quantum computer, publishing its hardware blueprints, control electronics and software openly.

Ottawa-based designer and manufacturer of fibre-optic components, test equipment and fibre-optic sensor systems, including polarization-maintaining components, attenuators, isolators and laser-to-fibre delivery optics.

Waterloo builder of in-line food inspection systems for meat processors, using its own patented spectrometers and hyperspectral imaging with AI to detect foreign material and grade product quality.

Waterloo company selling Page, an AI government-relations platform that monitors bills, hearings and regulations across 80+ jurisdictions and summarizes legislative activity with source citations.

Waterloo company building Anvil Checkpoint, an RF- and machine-learning-based test system that compares electronic assemblies against a known-good profile to detect hardware implants, counterfeit parts, tampering and manufacturing defects.

Toronto company building a large reconstruction model that turns 2D camera footage into navigable, photorealistic 3D video replays for live sports and coaching.

Builds quantum-enhanced LiDAR and 3D remote sensing, using time-binned single photons to pick signal out of noise for underwater, atmospheric and space applications.

Toronto company selling a physician-built AI medical scribe that generates SOAP notes, referral letters, OHIP billing suggestions and clinical insights for family doctors.

Toronto-based designer of optical engines, light sources and optical modules built on its Optical Interposer, a wafer-level platform combining electronic and photonic devices on one chip for AI systems and hyperscale data centres.

Mississauga-based provider of cloud electronic health record and care collaboration software for long-term and post-acute care providers and their hospital and payer partners.

Ottawa company running its own NVIDIA GPU edge nodes in colocation facilities, starting in Vancouver, Toronto and Montreal, and selling low-latency speech, language and text-to-speech inference through an OpenAI-compatible API.

Ottawa designer and manufacturer of laser material-processing systems, including RapiTrim laser resistor trimmers used on chip resistors, hybrid circuits and semiconductor wafers, and ProVia laser microvia drilling systems.

Mississauga-based commercial-stage medical device company making incision-free, MRI-guided ablation systems, including TULSA-PRO for prostate tissue and Sonalleve.

Toronto company whose cloud-based production platform turns off-the-shelf industrial robots into ready-to-deploy factory cells that manufacture building components for homebuilders, with plants in Edmonton and Calgary.

A clinical-stage biotech whose ProteinStudio platform combines machine learning, structural biology and atomic-level molecular simulation to design peptide therapeutics and peptide-drug conjugates.

Toronto company developing Protexxa Defender, a SaaS platform that finds employees' leaked credentials and dark-web exposure, scores cyber hygiene and guides remediation. It also sells consulting, managed detection and response, incident response and training services.

Toronto company selling AI co-pilots for construction pre-construction estimating, reviewing drawings, specs and contracts to flag missing scope, risky clauses and scope gaps before change orders occur.

London, Ontario based provider of cloud enterprise asset management, maintenance, budgeting, GIS and permitting software plus advisory services to local governments, schools and utilities across North America.

Develops microsatellite-based quantum key distribution systems that exchange encryption keys between satellites and ground stations, securing communications against quantum-computer attacks.

Builds machine learning software and IP for software-defined radios, covering RF signal sensing, classification and intelligent radio. Its quantum work is a federally backed quantum algorithm for radio signal sensing.

Waterloo developer of CasQade, a cryptographic-agility platform that moves systems to post-quantum cryptography and swaps encryption algorithms without downtime, offered alongside its AtlasAI data-analysis platform.

Toronto company that owns and operates nine colocation data centres in Toronto, Ottawa, London, Calgary and Edmonton, bought from Rogers in 2025, and sells colocation, virtual private and private cloud, object storage, backup and disaster-recovery services from them.

Sells the QiSpace platform for quantum-secure communications — post-quantum asymmetric encryption, symmetric encryption, and quantum-entropy key distribution.

Builds quantum-safe key distribution for existing networks, centred on its patented Distributed Symmetric Key Establishment (DSKE) protocol and Symmetric-Key Distribution System.

Designs and builds microchip sets for cryogenic and superconducting environments, including amplifiers that carry qubit readout signals from near absolute zero to room temperature.

Ottawa-based developer and manufacturer of co-packaged optical interconnects whose ODIN platform integrates lasers, modulators, photodetectors and drivers to move data between chips in AI and data centre systems.

Ottawa-based manufacturer of modular oceanographic instruments - sensors and data loggers measuring temperature, depth, salinity, dissolved gases and pH for marine and freshwater research.

Waterloo company offering superconducting circuit design, chip fabrication and cryogenic characterization as a service, for quantum and AI-inspired classical computing hardware.

Hamilton company selling Resiliocs Intelligence, an AI-powered SaaS platform that quantifies physical climate risk and financial impact for institutional investors, insurers and asset owners.

Burlington company selling Resso, an AI conversation-practice platform where users rehearse interviews, presentations and sales calls with lifelike AI avatars.

Toronto company selling a hyperspectral retinal imaging platform that uses AI to detect Alzheimer's-related amyloid biomarkers through a non-invasive eye scan, currently for research use only.

Ottawa company developing backup and recovery software for SaaS application data: automated daily backups, point-in-time restores and failover copies for platforms including Jira, Confluence, GitHub, Shopify and QuickBooks Online.

Retrofits light fixed-wing aircraft with its own autonomous flight software and flies them under remote-pilot supervision to carry cargo to remote, rural and northern communities.

Toronto company selling an AI recruiting platform that conducts voice-based candidate interviews around the clock, scores candidates against custom rubrics, and reaches them by SMS, WhatsApp and email.

Toronto company selling neural-network 'surrogate' models that replicate banks' proprietary derivatives pricing engines, cutting valuation and XVA risk-run times from hours to seconds.

Hamilton company building autonomous hospital service robots — disinfection, cleaning and delivery — with an in-house AI perception, navigation and task-management stack, operated by Robotech Labs Inc.

London, Ontario designer and manufacturer of optical instruments, including modular FTIR and Raman spectrometers, far-infrared terahertz spectroscopy systems, light sources, solar simulators and photovoltaic quantum-efficiency test equipment.

Kitchener company selling LabOS, an AI-powered lab operating system that connects instruments, ELN/LIMS systems and workflows, with Scibot handling QC flagging, inventory management and data analysis for life-science labs.

Kitchener, Ontario company selling an AI medical scribe built for veterinary medicine. It listens during appointments and client phone calls and produces structured, editable medical records that export into practice management systems.

Toronto company developing SD Elements, software that generates security and compliance requirements for developers and AI coding agents and tracks their implementation, alongside the Devici threat-modelling tool and hands-on application security training.

Toronto company selling an AI agent platform for utilities — Engineering, Regulatory and Customer Service agents that plan capital projects, draft regulatory filings and handle customer calls and chats.

Designs and manufactures modular, payload-agnostic fixed-wing uncrewed aircraft built with automated composites, configurable for reconnaissance, loitering strike, electronic warfare and counter-UAS roles.

Designs, builds and operates complete small satellite missions, offering space-proven bus platforms from 3 to 500 kg for Earth observation, communications and science customers worldwide. Spun out of the University of Toronto in 2026.

Toronto company selling a self-hosted platform that installs, orchestrates and governs more than 170 third-party AI and data tools inside a customer's own cloud or on-premises infrastructure, plus its own Kaji agent and an LLM gateway.

North York fabless semiconductor company making silicon MEMS micro-actuators that move the image sensor rather than the lens, delivering autofocus and optical image stabilisation in automotive, embedded-vision and AR/VR cameras.

Toronto company selling an AI Management System for hospitals, a platform health systems use to govern, monitor and orchestrate their agentic, generative and predictive AI tools in one place.

Builds thrust-vectoring inspection drones that make physical contact with structures to perform ultrasonic thickness testing and spot rust removal and coating.

Builds a geospatial data platform that lets organizations search, purchase, and integrate satellite and aerial Earth observation imagery from hundreds of sensors and data sources.

Builds quantum software tooling - compilers, circuit optimizers and simulators - plus a quantum-computing-as-a-service platform, and does quantum consulting and training for enterprise clients.

Ottawa company selling event-driven messaging infrastructure — event brokers available as a cloud service, software or hardware appliance, plus an event mesh, event portal and agent mesh — used to route real-time data between applications, clouds and data centres.

Toronto company (legally CircuitMind Inc.) selling AIMS, a physics-enhanced AI digital-twin platform that predicts and optimizes semiconductor fabrication recipes and processes.

Ottawa company selling an AI vision intelligence platform that unifies security-camera video with business data (POS, access control, HR) to detect theft, verify alarms and optimize retail and restaurant operations.

Toronto company selling an AI document-processing platform, built on Mocsy Inc., that triages, extracts and enriches data from insurance submissions such as ACORD forms, loss runs and SOVs for P&C carriers, MGAs and BPOs.

Waterloo company selling machine-learning and computer-vision powered digital twins - engineering-ready drawings, pole profiles and vegetation-encroachment assessment - for utility and telecom infrastructure.

Kingston, Ontario maker of Amplifi ID, a portable analyzer that pairs Raman spectroscopy with nanofabricated surface-enhanced Raman scattering (SERS) cartridges to identify chemical compounds in samples at the point of need.

London, Ontario manufacturer of multispectral and hyperspectral imaging systems built on pixelated multispectral filter array technology, including snapshot cameras, line-scan and drone cameras, LED illuminators and optical filters.

Legal AI company operating as Dialog Enterprises Inc., selling a contract suite that drafts, reviews, redlines and benchmarks contracts inside Microsoft Word. Founded in St. John's as Rally; now headquartered in Toronto.

Ottawa company that builds cross-domain security hardware for defence, government and critical infrastructure, including unidirectional gateways, an adaptive gateway and optical data diodes, and develops the Verity governance, risk and compliance software.

Ottawa designer and manufacturer of satellite communications test equipment and base-station subsystems, including the RLS-2100 radio link simulator and Classic Aero ground and aircraft earth station subsystems.

Toronto fabless analog, mixed-signal and silicon-photonics IP house designing SerDes, transceivers, micro-ring-modulator drivers and transimpedance amplifiers, plus custom silicon programs, for AI, data-centre and automotive interconnect.

Designs and manufactures precision satellite and stratospheric-balloon hardware - sub-arcsecond star cameras, cogless reaction wheels and attitude control systems - plus InSAR and AI analytics, from its Ayr, Ontario facility.

Hamilton biotech company using an AI-driven, biology-first platform called Mosaic to discover drug candidates against antibiotic-resistant infections and glioblastoma.

Ottawa company developing cyberstorage software that monitors enterprise file and object storage in real time to detect and stop ransomware and insider threats, automate response, keep air-gapped recovery copies and restore affected data.

Toronto company selling AI-powered digital wound care: smartphone-based calibrated wound imaging with tissue analytics drawn from what it calls the world’s largest wound imaging database, used by clinicians across the care continuum.

Waterloo developer of hardware video and audio CODEC semiconductor IP cores, covering MPEG-2, H.264 and H.265, plus system-on-module components and FPGA prototyping boards for broadcast, airborne, surveillance and medical video.

Toronto developer of model-specific AI inference silicon that hard-wires trained neural networks directly into custom chips. Its HC1 technology demonstrator is a TSMC 6nm part with 815 mm² of silicon and 53 billion transistors running Llama 3.1 8B.

Ottawa defence software company. Its FULCRUM platform validates, standardises and enriches ISR sensor and full-motion-video metadata so feeds from different airborne and ground platforms can be ingested by command-and-control systems.

Toronto company developing a WireGuard-based connectivity platform that links devices, cloud environments and workloads into encrypted peer-to-peer private networks with identity-based access policies, plus privileged access management and an AI gateway.

Toronto company selling an AI Scribe platform that turns patient conversations into structured clinical notes, plus clinical decision support, form filling and billing-code suggestions for physicians.

Ottawa semiconductor analysis firm performing in-depth chip teardowns and reverse engineering — circuit, layout and process analysis of processors, memory and advanced packaging — published as technology reports and market intelligence.

Global satellite operator running a geostationary fleet and building Telesat Lightspeed, a low Earth orbit broadband constellation. Dual-listed on Nasdaq and TSX.

London, Ontario company building the Lymphonator, an automated benchtop robotic scanning device that combines ultrasound imaging, robotics and AI to find lymph nodes in excised cancer tissue for pathology labs.

Toronto-based provider of digital clinical software - order sets, medication reconciliation, the Pharmapod platform and clinical workflow tools - used by hospitals, long-term care operators and pharmacies.

Toronto-headquartered channel-only Canadian cloud service provider offering private cloud, backup, disaster recovery and object storage, approved under Shared Services Canada frameworks.

Pembroke, Ontario company operating Earthfence, a deep-space radar for space situational awareness built on a 46-metre antenna in Canada, alongside compact space instruments including Argus infrared spectrometers.

Kitchener company selling an open-source operating system for AI researchers to train, fine-tune and evaluate models from local hardware to GPU clusters, plus Primus, an autonomous AI-researcher agent that runs experiments and writes papers.

Toronto company selling Simia, a patented real-time generative storytelling platform for connected TVs that creates interactive stories for kids and families as they watch.

Toronto internet-infrastructure company whose largest business, Tucows Domains, runs wholesale domain registrar platforms (OpenSRS, Enom, Ascio, Hover) and back-end registry services for top-level domains. It also owns the Ting fibre ISP, which it is divesting, and Wavelo telecom software.

Designs, manufactures and services aviation cabin-safety and crew-training equipment - evacuation training slides, bassinets, restraint kits and protective breathing equipment - plus defence flotation and protective textiles.

Ottawa company developing a vector and full-text search engine that keeps indexes on object storage and caches active data in memory and SSD, used as the retrieval layer for AI and search applications.

Quantum networking company building multiplexed atom-photon interconnect modules that link standalone neutral-atom quantum devices into networked systems over standard telecom fibre.

Toronto developer, designer, builder and operator of data centres, providing wholesale colocation and carrier-neutral connectivity from facilities in Ontario.

Mississauga optical thin-film coating manufacturer, vacuum-depositing anti-reflection, dichroic, beamsplitter, high-reflection dielectric, metal mirror, diamond-like-carbon and transparent conductive ITO coatings from UV to LWIR.

Ottawa-based developer of public safety software - computer-aided dispatch, records management, digital evidence and victim notification - for police, fire and EMS agencies, emergency communications centres, crime labs and court systems.

Kitchener company selling AI-powered video messaging and hosting for sales and go-to-market teams, including AI Avatars that generate personalized talking-head videos and an agentic Video Agent that sends them automatically.

Toronto generative AI company whose models animate and replace characters in video from a single image or reference footage. Sold through a consumer app, the PINOC character and motion tool, games and a developer API.

Toronto-based developer of software for hospitals, health systems and human services providers, covering care coordination, case management, referral and wait-list management, and operational analytics.

Mississauga-based developer of nanotechnology-based formulations that make existing agricultural pesticides and fungicides more effective and easier to apply.

Toronto company selling a platform for teams to design, build, test and deploy AI agents across voice, chat and connected devices for customer experience use cases.

Waterloo designer and assembler of benchtop additive-electronics machines - the V-One circuit board printer and the NOVA materials dispensing system - for printing circuits on rigid, flexible and stretchable substrates.

Waterloo-based developer of MicroSolid Printing, a transfer process for moving millions of micrometre-scale LEDs and other micro-semiconductor devices from wafer to backplane, for automotive, consumer and display applications.

Develops "Physical AI" software and a neural simulator aimed at powering autonomous long-haul trucks and, more recently, robotaxis.

Develops Rydberg atom quantum sensors that use cesium vapour cells to measure radio-frequency electromagnetic fields for RF test and measurement.

St. Catharines company building a proprietary computer-vision platform that measures road-sign retroreflectivity and readability from drive-sourced imagery, letting transportation agencies inspect sign networks without handheld devices or lane closures.

Richmond Hill engineer and manufacturer of OEM microscopy automation hardware, including laser autofocus sensors, modular microscopy systems and infrared confocal systems used in semiconductor wafer and flat-panel display inspection.

Toronto-based financial services company offering managed investing, self-directed trading, cryptocurrency, tax filing, and spending and saving products to Canadian retail clients.

Ottawa maker of light measurement and photometric imaging equipment — imaging photometers and colorimeters with its Photometrica analysis software — for display, lighting and luminance metrology.

Toronto company selling an AI platform that indexes, deduplicates and summarises medical, legal and billing records for insurance claims, sold to carriers, self-insured corporations, government agencies, defence counsel and medical experts.

Toronto company selling Dream by WOMBO, a generative AI art and video app, and WOMBO Meme, a lip-sync and meme-creation app, with over 200 million combined downloads.

Markham designer and manufacturer of laser diode modules and systems from 405 nm to 1064 nm, including line and cross generators, TEC-stabilised and fibre-coupled lasers, beam profilers and laser marking machines.

Toronto company selling xCognition and PLCfy, AI-based cognitive control software that automatically generates robot and PLC programs for industrial robots from natural-language instructions.

Builds scalable, modular, room-temperature photonic quantum computers and leads PennyLane, an open-source quantum programming library. Trades on Nasdaq and TSX as XNDU following a March 2026 SPAC merger.

Develops quantum-inspired and neural-network optimization software for financial firms, targeting portfolio optimization and derivative pricing for asset managers and capital markets.

Toronto company behind CLP, an open-source log archive platform that compresses logs and searches them without decompressing, deployed at petabyte scale in data centres and on edge devices.

Hamilton neurotechnology company selling Cognalyzer, an AI-powered EEG platform that quantifies how consumer products change mental state for cannabis, caffeine, nootropic and wearable brands.

Ottawa company developing behavioural-AI software that detects identity-based cyber threats and electronic interference such as GNSS jamming and spoofing, and fuses RF, drone and sensor data for counter-UAS situational awareness.